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dc.contributor.authorGates MC
dc.contributor.authorHumphry RW
dc.contributor.authorGunn GJ
dc.contributor.authorWoolhouse MEJ
dc.date.accessioned2014-11-24T12:34:15Z
dc.date.available2014-11-24T12:34:15Z
dc.date.issued2014
dc.identifier.citation45:110en_US
dc.identifier.urihttp://dx.doi.org/10.1186/s13567-014-0110-y
dc.identifier.urihttp://hdl.handle.net/11262/10531
dc.description.abstractMany economically important cattle diseases spread between herds through livestock movements. Traditionally, most transmission models have assumed that all purchased cattle carry the same risk of generating outbreaks in the destination herd. Using data on bovine viral diarrhoea virus (BVDV) in Scotland as a case example, this study provides empirical and theoretical evidence that the risk of disease transmission varies substantially based on the animal and herd demographic characteristics at the time of purchase. Multivariable logistic regression analysis revealed that purchasing pregnant heifers and open cows sold with a calf at foot were associated with an increased risk of beef herds being seropositive for BVDV. Based on the results from a dynamic within-herd simulation model, these findings may be partly explained by the age-related probability of animals being persistently infected with BVDV as well as the herd demographic structure at the time of animal introductions. There was also evidence that an epidemiologically important network statistic, “betweenness centrality” (a measure frequently associated with the potential for herds to acquire and transmit disease), was significantly higher for herds that supplied these particular types of replacement beef cattle. The trends for dairy herds were not as clear, although there was some evidence that open heifers and open lactating cows were associated with an increased risk of BVDV. Overall, these findings have important implications for developing simulation models that more accurately reflect the industry-level transmission dynamics of infectious cattle diseases.en_US
dc.language.isoenen_US
dc.relation.isformatof13845en_US
dc.relation.ispartofVeterinary Researchen_US
dc.rightsCopyright © 2014 Gates et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjectEpidemiologyen_US
dc.subjectCowsen_US
dc.subjectBovine viral diarrhoea virusen_US
dc.subjectBVDVen_US
dc.subjectCattle movementsen_US
dc.subjectVirus transmissionen_US
dc.titleNot all cows are epidemiologically equal: quantifying the risks of bovine viral diarrhoea virus (BVDV) transmission through cattle movementsen_US
dc.typeArticleen_US
dc.description.versionVersion of recorden


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