Browsing by Author "McNeilly TN"
Now showing items 1-14 of 14
-
Co-infection with Fasciola hepatica may increase the risk of Escherichia coli O157 shedding in British cattle destined for the food chain
Howell AK; Tongue SC; Currie C; Evans J; Williams DJL; McNeilly TN (2017)Escherichia coli O157 is a zoonotic bacterium that can cause haemorrhagic diarrhoea in humans and is of worldwide public health concern. Cattle are considered to be the main reservoir for human infection. Fasciola hepatica ... -
Complex responses to movement-based disease control: when livestock trading helps
Prentice JC; Marion G; Hutchings MR; McNeilly TN; Matthews L (2017)Livestock disease controls are often linked to movements between farms, for example, via quarantine and pre- or post-movement testing. Designing effective controls, therefore, benefits from accurate assessment of herd-to-herd ... -
Escherichia coli 0157:H7 colonization in cattle following systemic mucosal immunization with purified H7 flagellin
McNeilly TN; Naylor SW; Mahajan A; Mitchell MC; McAteer S; Deane D; Smith DGE; Low JC; Gally DL; Huntley JF (2008) -
Estimating genetic and phenotypic parameters of cellular immune-associated traits in dairy cows
Denholm SJ; McNeilly TN; Banos G; Coffey MP; Russell GC; Bagnall A; Mitchell MC; Wall E (2017)Data collected from an experimental Holstein-Friesian research herd were used to determine genetic and phenotypic parameters of innate and adaptive cellular immune-associated traits. Relationships between immune-associated ... -
Exposure to viral and bacterial pathogens among Soay sheep (Ovis aries) of the St Kilda archipelago
Graham AL; Nussey DH; Lloyd-Smith JO; Longbottom D; Maley M; Pemberton JM; Pilkington JG; Prager KC; Smith L; Watt KA; Wilson K; McNeilly TN; Brulisauer F (2016)We assessed evidence of exposure to viruses and bacteria in an unmanaged and long-isolated population of Soay sheep (Ovis aries) inhabiting Hirta, in the St Kilda archipelago, 65 km west of Benbecula in the Outer Hebrides ... -
The feasibility of testing whether Fasciola hepatica is associated with increased risk of verocytotoxin producing Escherichia coli O157 from an existing study protocol
Hickey GL; Diggle PJ; McNeilly TN; Tongue SC; Chase-Topping ME; Williams DJL (2015)The parasite Fasciola hepatica is a major cause of economic loss to the agricultural commu-nity worldwide as a result of morbidity and mortality in livestock, including cattle. Cattle arethe principle reservoir of ... -
Genetic parameters of cellular immune traits in UK Holstein-Friesian dairy cows (Bos taurus)
Denholm SJ; McNeilly TN; Banos G; Coffey MP; Russell GC; Bagnall A; Mitchell MC; Wall E (John Wiley & Sons Ltd., 01/12/2014)A previous study in dairy cows identified associations between a number of cellular immune traits within the blood and important health traits, including CD4:CD8 T cell ratios and subclinical mastitis, % CD8 T cells and ... -
Genetic parameters of immune traits in dairy cattle
Denholm SJ; McNeilly TN; Banos G; Coffey MP; Russell GC; Bagnall A; Mitchell MC; Wall E (American Society of Animal Science, 17/08/2014)Previous work has identified a number of immune traits which are associated with dairy cow health. The purpose of the present study was to determine the genetic parameters of these immune traits. Blood samples were ... -
IgA and IgG antibody responses following systemic immunization of cattle with native H7 flagellin differ in epitope recognition and capacity to neutralise TLR5 signalling
McNeilly TN; Mitchell MC; Nisbet AJ; McAteer S; Erridge C; Inglis NF; Smith DGE; Low JC; Gally DL; Huntley JF; Mahajan A (2010)Systemic immunization of cattle with H7 flagellin results in induction of both H7-specific IgA and IgG antibodies but only partially protects against subsequent colonization with Escherichia coli O157:H7. Recent studies ... -
Immune-associated traits measured in milk of Holstein-Friesian cows as proxies for blood serum measurements
Denholm SJ; McNeilly TN; Banos G; Coffey MP; Russell GC; Bagnall A; Mitchell MC; Wall E (2018)Previous work has highlighted that immune-associated (IA) traits measurable in blood are associated with health, productivity and reproduction in dairy cows. The aim of the present study was to determine relationships ... -
Immunization of cattle with a combination of purified intimin-531, EspA and Tir significantly reduces shedding of Escherichia coli O157:H7 following oral challenge
McNeilly TN; Mitchell MC; Rosser T; McAteer S; Low JC; Smith DGE; Huntley JF; Mahajan A; Gally DL (2010) -
Is it feasible to test if liver fluke (Fasciola hepatica) is associated with increased risk of verocytotoxin producing Escherichia coli O157 from an existing study?
Hickey GL; Diggle PJ; McNeilly TN; Tongue SC; Chase-Topping ME; Williams DJL (ISVEE, 11/2015)The liver fluke parasite, Fasciola hepatica, is a major cause of economic loss to cattle industries worldwide. Cattle are also the principle reservoir of Verocytotoxigenic Escherichia coli O157 (VTEC O157), an important ... -
Simple methods for measurement of bovine mucosal antibody responses in vivo
McNeilly TN; Naylor SW; Mitchell MC; McAteer SP; Mahajan A; Smith DGE; Gally DL; Low JC; Huntley JF (2007) -
Strain-dependent cellular immune responses in cattle following Escherichia coli O157:H7 colonization
Corbishley A; Ahmad NI; Hughes K; Hutchings MR; McAteer SP; Connelley TK; Brown H; Gally DL; McNeilly TN (2014)Enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes hemorrhagic diarrhea and potentially fatal renal failure in humans. Ruminants are considered to be the primary reservoir for human infection. Vaccines that reduce ...